Contains 5 Mg Ivermectin/ml
ANADA 200-272, Approved by the FDA
Kills: Roundworms (including Brown Stomach Worms), Lungworms, Grubs,
Sucking Lice, Biting Lice, Mange Mites, Horn Flies
Consult your veterinarian for
assistance in the diagnosis, treatment and control of parasitism.
Ivermectin (ivermectin) Pour-On delivers internal and external parasite control in
one convenient low-volume application.
Ivermectin Pour-On Indications
Ivermectin Pour-On applied at the recommended dose level of 500
mcg/kg is indicated for the effective control of these parasites.
Ostertagia ostertagi (including inhibited stage) (adults and L4), Haemonchus placei (adults and L4), Trichostrongylus axei (adults and L4), T. colubriformis (adults and L4), Cooperia spp. (adults and L4), Oesophagostomum radiatum (adults and L4), Strongyloides papillosus (adults), Trichuris
Dictyocaulus viviparus (adults and L4)
Cattle Grubs (parasitic Stages)
hypoderma Bovis, H. Lineatum
Sarcoptes scabiei var. bovis
Linognathus vituli, Haematopinus eurysternus, Damalinia bovis,
Ivermectin Pour-On has been proved to effectively control
infections and to protect cattle from re-infection with Ostertagia
ostertagi, Oesophagostomum radiatum, Haemonchus placei, Trichostrongylus
axei, Cooperia punctata and Cooperia oncophora for 14 days
Treatment For Cattle For Horn Flies
Ivermectin Pour-On controls horn flies (Haematobia irritans)
for up to 28 days after dosing. For best results, Ivermectin Pour-On
should be part of a parasite control program for both internal and
external parasites based on the epidemiology of these parasites. Consult
a veterinarian or an entomologist for the most effective timing of
The dose rate is 1 mL for each 22 lb of body weight. The
formulation should be applied along the topline in a narrow strip
extending from the withers to the tailhead.
Collapsible Packs (33.8 fl oz/1 liter pack, 84.5 fl oz/2.5
liter pack, 169 fl oz/5 liter pack with dosing gun/applicator) -
Because of the solvents used in Ivermectin Pour-On, the applicator gun
from Simcro Tech, or equivalent, is recommended. Other applicators may
exhibit compatibility problems resulting in locking, incorrect dosage or
leakage. Remove the shipping cap from the backpack container and
replace with the vent cap provided. Attach the hose from the automatic
dosing equipment to the outlet from the vent cap. Follow the applicator
gun manufacturer's directions for priming the gun, adjusting the dose,
and care of the applicator gun following use.
Container (676 fl oz/20 liter container with draw-off device
and dosing gun/applicator) - Because of the solvents used in
Ivermectin Pour-On, the draw-off device and applicator gun from Simcro
Tech, or equivalent, is recommended. Other applicators may exhibit
compatibility problems resulting in locking, incorrect dosage or
leakage. Screw Feedlot pack cap and dip tube onto the 20 liter drum
ensuring a tight fit. Connect the long 3m feed tube at one end to the
spigot on the Feedlot pack cap and the other end to the applicator gun.
Then follow the applicator gun manufacturer's directions for priming the
gun, adjusting the dose, and care of the applicator gun following use.
When the interval between use of the applicator gun is expected to
exceed 12 hours, disconnect the gun, draw off tubing and dip tub and
cap from the product container, empty the product from the gun and
tubing back into the container and replace the shipping cap.
220 lb (100 kg)
330 lb (150 kg)
440 lb (200 kg)
550 lb (250 kg)
660 lb (300 kg)
770 lb (350 kg)
880 lb (400 kg)
990 lb (450 kg)
1100 lb (500 kg)
Mode Of Action
Ivermectin is a member of the macrocylic lactone class of
endectocides which have a unique mode of action. Compounds of the class
bind selectively and with high affinity to glutamate-gated chloride ion
channels which occur in invertebrate nerve and muscle cells.
This leads to an increase in the permeability of the cell membrane
to chloride ions with hyperpolarization of the nerve or muscle cell,
resulting in paralysis and death of the parasite. Compounds of this
class may also interact with other ligand-gated chloride channels, such
as those gated by the neurotransmitter gamma-aminobutyric acid (GABA).
The margin of safety for compounds of this class is attributable
to the fact that mammals do not have glutamate-gated chloride channels,
the macrocylic lactones have a low affinity for other mammalian
ligand-gated chloride channels and they do not readily cross the
Studies conducted in the U.S.A. have demonstrated the safety
margin for ivermectin. Based on plasma levels, the topically applied
formulation is expected to be at least as well tolerated by breeding
animals as is the subcutaneous formulation which had no effect on
Cattle must not be treated within 48 days of slaughter for human
consumption. Because a withdrawal time in milk has not been established,
do not use in female dairy cattle of breeding age. A withdrawal period
has not been established for this product in preruminating calves. Do
not use in calves to be processed for veal.
WARNING! NOT FOR USE IN HUMANS
This product should not be applied to self or others because it
may be irritating to human skin and eyes and absorbed through the skin.
To minimize accidental skin contact, the user should wear a long-sleeved
shirt and rubber gloves. If accidental skin contact occurs, wash
immediately with soap and water. If accidental eye exposure occurs,
flush eyes immediately with water and seek medical attention.
Keep This And All Drugs Out Of The Reach Of Children.
Warning! Flammable! Keep Away From Heat, Sparks, Open Flame, And
Other Sources Of Ignition.
The Material Safety Data Sheet (msds) Contains More Detailed
Occupational Safety Information. To Report Adverse Effects, Obtain An
Msds, Or For Assistance Call Aspen Veterinary At (800) 378-8551.
Store Away From Excessive Heat (104°f/40°c) And Protect From
Use only in well-ventilated areas or outdoors.
Close container tightly when not in use.
Cattle should not be treated when hair or hide is wet since
reduced efficacy may be experienced.
Do not use when rain is expected to wet cattle within six hours
This product is for application to skin surface only. Do not give
orally or parenterally.
Cloudiness in the formulation may occur when Ivermectin Pour-On is
stored at temperatures below 32°F. Allowing to warm at room temperature
will restore the normal appearance without affecting efficacy.
Antiparasitic activity of ivermectin will be impaired if the
formulation is applied to areas of the skin with mange scabs or lesions,
or with dermatoses or adherent materials, e.g., caked mud or manure.
Ivermectin has been associated with adverse reactions in sensitive
dogs; therefore, Ivermectin Pour-On is not recommended for use in
species other than cattle.
When To Treat Cattle With Grubs
Ivermectin Pour-On effectively controls all stages of cattle
grubs. However, proper timing of treatment is important. For the most
effective results, cattle should be treated as soon as possible after
the end of the heel fly (warble fly) season. While this is not peculiar
to ivermectin, destruction of Hypoderma larvae (cattle grubs) at
the period when these grubs are in vital areas may cause undesirable
host-parasite reactions. Killing Hypoderma lineatum when it is in
the esophageal tissues may cause bloat: killing H. bovis when it
is in the vertebral canal may cause staggering or paralysis. Cattle
should be treated either before or after these stages of grub
Cattle treated with Ivermectin Pour-On at the end of the fly
season may be re-treated with ivermectin during the winter without
danger of grub-related reactions. For further information and advice on a
planned parasite control program, consult your veterinarian.
Studies indicate that when ivermectin comes in contact with the
soil, it readily and tightly binds to the soil and becomes inactive over
time. Free ivermectin may adversely affect fish or certain aquatic
organisms. Do not permit cattle to enter lakes, streams or ponds for at
least six hours after treatment. Do not contaminate water by direct
application or by the improper disposal of drug containers. Dispose of
containers in an approved landfill or by incineration.
As with other avermectins, ivermectin is excreted in the dung of
treated animals and can inhibit the reproduction and growth of pest and
beneficial insects that use dung as a source of food and for
reproduction. The magnitude and duration of such effects are species and
life-cycle specific. When used according to label directions, the
product is not expected to have an adverse impact on populations of
Ivermectin Pour-On is available in a 8.5 fl oz/250 mL bottle, in a
33.8 fl oz/1 L collapsible pack, in an 84.5 fl oz/2.5 L, in a 3.785 L
(1 gal) bottle, in a 169 fl oz/5 L collapsible pack, a 676 fl oz/20 L
container or a 25 L carboy intended for use with appropriate automatic
Manufactured for: Aspen Veterinary Resources®, Ltd., Kansas City, MO 64161
Manufactured by: Norbrook Laboratories Ltd., Newry, Co. Down, BT35
6PU, Northern Ireland
Made in the U.K.
250 mL (8.5 fl oz)
1 L (33.8 fl oz)
84.5 fl oz (2.5 L)
3.785 L (1 Gal)
5 L (169 fl oz)
676 fl oz (20 L)
25 L (6.6 gal)