Nonencapsulated Live Culture
Anthrax Spore Vaccine is prepared with a relatively nonpathogenic, noncapsulated variant strain of B. anthracis, originally developed at the Onderstepoort Laboratory, Pretoria, South Africa. Further work was conducted in England, India and in many other countries. Vaccine Strain is Sterne 34F2. The vaccine is a suspension of viable Bacillus anthracis spores in saponin. It is tested for purity, identity, dissociation, spore count, and safety prior to release for sale.
Anthrax occurs in all parts of the world. It is an acute, febrile infection that has a rapidly fatal course. It is one of the oldest and most destructive diseases of livestock.
Anthrax is caused by Bacillus anthracis. It is highly virulent, and once access to the animal's body is gained, it multiplies quickly, invades the blood stream and produces a rapidly fatal blood infection. In the presence of oxygen the bacilli form spores which are remarkably tenacious, highly resistant to heat, low temperatures and chemical disinfectants, retaining viability for many years in both soil and water and upon hides or contaminated objects held in storage. Animals of all species are susceptible to anthrax to some degree. Cattle, horses, sheep and goats are those most frequently affected. Swine apparently possess some natural resistance but anthrax does occasionally appear in them. Dogs, cats and wild animals may become infected under some conditions. Mice and guinea pigs are highly susceptible.
Symptoms of anthrax vary according to the specie of animals and the acuteness of the attack. The average period of incubation ranges from 24 hours to as much as 5 days or more. The acute form, most common in cattle, sheep and goats is characterized by its sudden onset and rapidly fatal course. Affected animals may present with sudden staggering, difficult respiration, trembling, collapse with convulsive movements and death, which may also occur without evidence of illness. Swellings sometime appear in different parts of the body, such as the throat and tongue, particularly in affected swine. Upon or near death, blood may ooze from body openings.
DIRECTIONS WHEN TO VACCINATE
Do not vaccinate within 42 days before slaughter.
In those areas where anthrax is known to be a problem, it is advisable to revaccinate annually approximately 4 weeks prior to the time the disease usually appears.
For control of outbreaks, vaccination of all animals not showing symptoms is recommended. Not all animals will be protected by this procedure but taking action as suggested may stop further spread of the disease. It is also recommended that animals showing symptoms be isolated and treated with antibiotics as permitted.
DOSAGE AND ADMINISTRATION
Inject 1 ml subcutaneously into each animal. Revaccinate in 2 - 3 weeks in heavily contaminated areas.
The region of the neck just in front of the shoulder is a convenient site for administering the vaccine to cattle, swine, sheep, and goats. Horses may be vaccinated subcutaneously in the middle portion of the neck or in the brisket at a time when the animals are not being heavily worked. A light to moderate swelling may appear at the site of injection. This will disappear after several days.
Anaphylactoid reactions may occur following administration of product of this nature. If noted, administer adrenaline or equivalent.
ACCIDENTAL HUMAN EXPOSURE
In the event of accidental human exposure, consult a physician.
1. Store at 2° to 7°C. Do not freeze.
2. Shake well before use.
3. Do not use disinfectants to sterilize equipment.
4. Use entire contents when first opened.
5. Burn, autoclave or chemically disinfect this container and all unused contents.
6. Animals being vaccinated or recently vaccinated should not receive antibiotics, as antibiotics will interfere with effective vaccination.
7. Conveniently packaged in various sizes.
USDA Code 1011.00
U.S. Vet. License No. 188
COLORADO SERUM COMPANY, 4950 York St., Denver, Colorado 80216
Contact us for information on other Colorado Serum Company products.
Fine Veterinary Biologicals since 1923.
FOR VETERINARY USE ONLY
NAC No.: 11010002