BRUCELLA ABORTUS VACCINE STRAIN RB-51, LIVE CULTURE
Brucellosis or “Bangs Disease” is a contagious disease of cattle caused by the gram negative bacterium Brucella abortus.
The disease in animals is characterized by abortion, retained placenta
and to a lesser extent, orchitis and infection of the accessory sex
glands in males. Brucellosis primarily affects cattle, buffalo, bison,
pigs, sheep, goats, dogs, elk and occasionally horses. The disease in
man is called Undulant Fever.
Control and elimination of this disease in cattle involves testing and culling reactors and vaccinating healthy females.
Brucella Abortus Vaccine, Strain RB-51, Live Culture,
Code 1261.00 was first licensed in 1996. It has been used exclusively
since than as part of the federal program to eradicate brucellosis from
the United States because it is safe, effective and does not interfere
with diagnostic testing for infection.
Brucella Abortus Vaccine, RB-51, is the result of
research, development and production efforts by both the public and
private sectors. It was selected as a stable strain which produces
protective immunity while not inducing antibodies which react in
standard serological tests. RB-51 has been tested to verify safety,
efficacy and to demonstrate that there is no serological reaction in
The Animal and Plant Health Inspection Service of the
US Department of Agriculture with cooperation of the Centers for
Disease Control conducted a risk analysis to assess the potential effect
of this product on the safety of animals, public health, and the
environment. Based on the risk analysis, APHIS prepared an environmental
assessment (EA). APHIS concluded that the licensure of this veterinary
biological product would not significantly affect the quality of the
human environment (FONSI).
Distribution in the United States shall be limited to
authorized recipients designated by proper state officials under such
additional conditions as these authorities may require.
For use by or under the supervision of a veterinarian.
For use in healthy female cattle 4 to 12 months of age as an aid in the prevention of infection and abortion caused by Brucella abortus.
Do not administer to pregnant cows.
Do not vaccinate within 3 weeks before slaughter.
Rehydrate with accompanying vial of sterile diluent supplied as a
component part of this package. Shake well after rehydration. Administer
2.0 ml subcutaneously.
Anaphylactoid reaction may occur following
administration of products of this nature. If noted, administer
adrenalin or equivalent.
1. Store at 2° to 7° C.
2. Use entire contents when first rehydrated.
3. Burn, autoclave or chemically disinfect this container and all unused contents.
4. In the case of accidental human exposure contact a physician.
Warning: This organism is Rifampin and Penicillin resistant.
5. Diluent is buffered solution specifically prepared
for use with this vaccine. Use only this diluent to assure viability of
6. Conveniently packaged in 25 dose, and 5 dose sizes.
USDA Code 1261.00
U.S. Vet. License No. 188
PROFESSIONAL BIOLOGICAL COMPANY, 4950 York Street, Denver, CO. 80216 U.S.A.
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FOR VETERINARY USE ONLY
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