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ACTIONS It has been demonstrated that selenium and tocopherol
exert physiological effects and that these effects are intertwined with
sulfur metabolism. Additionally, tocopherol appears to have a
significant role in the oxidation process, thus suggesting an
interrelationship between selenium and tocopherol in overcoming
sulfur-induced depletion and restoring normal metabolism. Although oral
ingestion of adequate amounts of selenium and tocopherol would seemingly
restore normal metabolism, it is apparent that the presence of sulfur
and, perhaps other factors interfere during the digestive process with
the proper utilization of selenium and tocopherol. When selenium and
tocopherol are injected, they bypass the digestive process and exert
their full metabolic effects promptly on cell metabolism.
Anti-inflammatory action has been demonstrated by selenium-tocopherol in
the Selye Pouch Technique and experimentally induced polyarthritis
study in rats.
INDICATIONS MU-SE (selenium, vitamin E) is recommended for
the prevention and treatment of STD syndrome in weanling calves and
breeding beef cattle. Clinical signs are: Stiffness and lameness;
chronic, persistent diarrhea; unthriftiness, abortions and/or weak
CONTRAINDICATION Do not use in adult dairy cattle. Premature
births and abortions have been reported in dairy cattle injected with
this product during the third trimester of pregnancy.
WARNINGS Anaphylactoid reactions, some of which have been
fatal, have been reported in cattle administered the MU-SE product.
Signs include excitement, sweating, trembling, ataxia, respiratory
distress, and cardiac dysfunction.
Use only as directed in weanling calves and breeding beef cows.
Discontinue use 30 days before the treated cattle are slaughtered for
caution selenium Is Toxic If Administered In Excess. A Fixed
Dose Schedule Is Therefore Important (read Package Insert For Each
Selenium-tocopherol Product Carefully Before Using).
precautions selenium-tocopherol Deficiency (std) Syndrome
Produces A Variety And Complexity Of Symptoms Often Interfering With A
Proper Diagnosis. Even In Selenium Deficient Areas There Are Other
Disease Conditions Which Produce Similar Clinical Signs. It Is
Imperative That All These Conditions Be Carefully Considered Prior To
The Treatment Of Std Syndrome. Selenium Levels, Elevated Sgot, And Creatine
Serum Levels May Serve As Aids In Arriving At A Diagnosis Of Std, When
Associated With Other Indices.
important Use Only The Selenium-tocopherol Product Recommended
For Each Species. Each Formulation Is Designed For The Species
Indicated To Produce The Maximum Efficacy And Safety.
how Supplied 100 Ml Sterile, Multiple Dose Vial.
storage Store Between 2° And 30°c (36° And 86°f). Protect From
NADA # 30-314, Approved by FDA
Copyright © 1985, 1996, 1998, Schering-Plough Animal Health Corp.,
Union, NJ 07083. All rights reserved.
Made in Germany.
22233203 Rev. 10/98
US 1492 USA006576LA