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ZIMECTERIN® GOLD PASTE
(ivermectin 1.55%/praziquantel 7.75%) Paste
REMOVES ROUNDWORMS, TAPEWORMS AND BOTS WITH A SINGLE DOSE.
FOR ORAL USE IN HORSES ONLY
CONTENTS WILL TREAT UP TO 1250 lb BODY WEIGHT.
NADA 141-214, Approved by FDA
INDICATIONS: Consult your veterinarian for assistance in the diagnosis, treatment, and control of parasitism. ZIMECTERIN® GOLD (ivermectin/praziquantel) Paste provides effective treatment and control of the following parasites in horses. Tapeworms - Anoplocephala perfoliata, Large Strongyles (adults) - Strongylus vulgaris (also early forms in blood vessels), S. edentatus (also tissue stages), S. equinus, Triodontophorus spp. including T. brevicauda and T. serratus and Craterostomum acuticaudatum; Small Strongyles (adults, including those resistant to some benzimidazole class compounds) - Coronocyclus spp. including C. coronatus, C. labiatus and C. labratus, Cyathostomum spp. including C. catinatum and C. pateratum, Cylicocyclus spp. including C. insigne, C. leptostomum, C. nassatus, and C. brevicapsulatus, Cylicodontophorus spp., Cylicostephanus spp., including C. calicatus, C. goldi, C. longibursatus and C. minutus, and Petrovinema poculatum; Small Strongyles - Fourth-stage larvae; Pinworms (adults and fourth-stage larvae) - Oxyuris equi; Ascarids (adults and third- and fourth-stage larvae) - Parascaris equorum; Hairworms (adults) - Trichostrongylus axei; Large-mouth Stomach Worms (adults) - Habronema muscae; Bots (oral and gastric stages) - Gasterophilus spp. including G. intestinalis and G. nasalis; Lungworms (adults and fourth-stage larvae) - Dictyocaulus arnfieldi; Intestinal Threadworms (adults) - Strongyloides westeri; Summer Sores caused by Habronema and Draschia spp. cutaneous third-stage larvae; Dermatitis caused by neck threadworm microfilariae, Onchocerca sp.
DOSAGE AND ADMINISTRATION: The
syringe contains sufficient paste to treat one 1250 lb horse at the
recommended dose rate of 91 mcg ivermectin per lb (200 mcg/kg) body
weight and 454 mcg praziquantel per lb (1 mg/kg) body weight. Each
weight marking on the syringe plunger delivers enough paste to treat 250
lb body weight.
(1) While holding plunger, turn the knurled ring on the
plunger 1/4 turn to the left and slide it so the side nearest the
barrel is at the prescribed weight marking. (2) Lock the ring in place
by making a 1/4 turn to the right. (3) Make sure that the horse’s mouth
contains no feed. (4) Remove the cover from the tip of the syringe. (5)
Insert the syringe tip into the horse’s mouth at the space between the
teeth. (6) Depress the plunger as far as it will go, depositing paste on
the back of the tongue. (7) Immediately raise the horse’s head for a
few seconds after dosing.
PARASITE CONTROL PROGRAM: All horses
should be included in a regular parasite control program with
particular attention being paid to mares, foals and yearlings. Foals
should be treated initially at 2 months of age, and routine treatment
repeated as appropriate. Consult your veterinarian for a control program
to meet your specific needs.
ZIMECTERIN® GOLD Paste
effectively controls gastrointestinal cestodes, nematodes and bots of
horses. Regular treatment will reduce the chances of verminous arteritis
caused by Strongylus vulgaris.
PRODUCT ADVANTAGES: Broad-spectrum Control - ZIMECTERIN® GOLD Paste kills important internal parasites, including tapeworms, bots and the arterial stages of S. vulgaris, with a single dose. ZIMECTERIN® GOLD Paste is a potent antiparasitic agent that is neither a benzimidazole nor an organophosphate.
ANIMAL SAFETY: ZIMECTERIN® GOLD Paste may be used in horses two months of age or older. ZIMECTERIN®
GOLD has not been tested in foals younger than two months of age, mares
at or near the time of breeding, pregnant or lactating mares, and
breeding stallions. ZIMECTERIN® GOLD
Paste, when tested at 1, 3 and 5-times the maximum recommended dose
every two weeks in 5-month old foals, and at 10-times the maximum
recommended dose in a separate study, did not elicit any adverse
clinical signs of toxicity. In a foal safety study in younger animals,
ZIMECTERIN® GOLD Paste was found safe up to 3-times the maximum recommended dose in 2-month old foals.
WARNING: Do not use in horses intended for human consumption.
Not for use in humans. Keep this and all drugs out of reach of children.
Refrain from smoking and eating when handling. Wash
hands after use. Avoid contact with eyes. The Material Safety Data Sheet
(MSDS) contains more detailed occupational safety information. To
report adverse reactions in users, to obtain more information, or to
obtain a MSDS, contact Merial at 1-888-637-4251.
PRECAUTIONS: ZIMECTERIN® GOLD (ivermectin/praziquantel) Paste has been formulated specifically for use in horses only. This product should not be used in other animal species as severe adverse reactions, including fatalities in dogs, may result.
Post-Approval Experience: Although
not all adverse reactions are reported, the following reactions are
based on voluntary post-approval drug experience reporting. There have
been rare reports of swelling and irritation of the mouth, lips, and
tongue following administration of ZIMECTERIN® GOLD. These reactions have been transitory in nature.
Environmental Safety: Ivermectin and
excreted ivermectin residues may adversely affect aquatic organisms. Do
not contaminate ground or surface water. Dispose of the syringe in an
approved landfill or by incineration.
Information For Horse Owners:
Swelling and itching reactions after treatment with ivermectin have
occurred in horses carrying heavy infections of neck threadworm (Onchocerca sp.)
microfilariae. These reactions were most likely the result of
microfilariae dying in large numbers. Symptomatic treatment may be
advisable. Consult your veterinarian should any such reactions occur.
Healing of summer sores involving extensive tissue changes may require
other appropriate therapy in conjunction with treatment with ZIMECTERIN®
GOLD Paste. Reinfection, and measures for its prevention, should also
be considered. Consult your veterinarian if the condition does not
STORAGE: Store up to 86°F (30°C). Transient exposure to temperatures up to 104°F (40°C) is permitted.
U.S. Pat. Pending
®ZIMECTERIN is a registered trademark and the Horse Head Logo is a trademark of Merial.
©2010 Merial. All rights reserved.
Marketed by Merial LLC, Duluth, GA 30096-4640
Made in Brazil
SEALED FOR SECURITY. IF BROKEN, DO NOT ACCEPT.
Net Wt. 0.26 oz (7.35 g)
20 Oral SyringesOne Counter DisplayContaining 20 x 0.26 oz (7.35 g) Ivermectin/Prazinquantel Paste
Pack of 40 Oral SyringesEach Containing 0.26 oz (7.35 g) Ivermectin/Prazinquantel Paste
Pack of 10x6 Oral SyringesEach Containing 0.26 oz (7.35 g) Ivermectin/Prazinquantel Paste
Pack of 216 Oral SyringesEach Containing 0.26 oz (7.35 g) Ivermectin/Prazinquantel Paste
NAC No.: 11111033