| Canine Parvo Virus
Canine Parvo virus is a viral disease that is the leading killer of puppies in the United States. Most cases are seen in puppies younger than 6 months of age, with the most severe being seen in puppies 12 weeks of age or less.
Up until the late 1970s, Parvo was not a problem in the United States. In 1998, the original strain of CPV-2 appeared, possibly as a variant of a related virus of another host, possibly from feline panleukopenia virus (FPV), but this strain was later replaced by CPV-2E. In 1986, another variation called CPV-2B appeared. Today, CPV-2B has largely replaced the previous strains as the most common isolate. Since all of these strains are similar, we will lump them together and refer to them as CPV-2 (Parvo).
There is currently some discussion that there may be other strains that are beginning to emerge. However results of studies that have been conducted have shown that there has not been any change in the Canine Parvo Virus since it mutated to the CPV-2b strain. The outbreaks of Parvo infection in vaccinated puppies in kennels are caused by inadequate vaccination. This is due to in effective vaccines being administered and/or an improper vaccination schedule being followed.
The disease enters through the nose or mouth. The normal incubation period is from 4 days; however active excretion of Parvo virus can begin after the third day of exposure. Upon entering the body, the virus attacks the nearest rapidly dividing cells, the lymph nodes of the throat. Here the virus replicates enough to go into the bloodstream where it seeks other rapidly dividing cells, such as bone marrow or intestinal cells. Here is where the virus knocks out the crucial number of white blood cells, thus enabling it to destroy the GI tract. Inevitably diarrhea, nausea, vomiting and bloody stool are a direct result. Death will result from either extreme fluid loss and dehydration or septic toxins entering the entire body because of the break down of intestinal barriers.
Treatment of an infected dog will include fluid therapy in the early stages, and drugs to control vomiting and diarrhea. The survival rate of an infected dog is low, however with the vigorous treatment; it is possible for the dog to survive. There is no one product or miracle cure for Parvo. When treating, realize that the treatment is for the effects of Parvo, because once Parvo has set up in its host, it is incurable. However prevention can be obtained through vaccination and sanitation. Contrary to popular belief, most of the canine parvo virus vaccines available, either as a single antigen or multiple antigen combination vaccines are inadequate in their ability to protect young puppies (16 weeks of age) against canine Parvo virus infection. This is especially true in breeding kennels. This is proven by the fact that puppies are dying from parvo virus disease even after repeated vaccinations.
It has been proven that a high level of protection in young puppies of this age group, during times of exposure, NeoPar is 700% to 6500% more potent than any of the other Parvo vaccines available. And can be given safely at 35 and 49 days of age. Protecting them sooner and against all known strains of the Parvo virus with NeoPar, a more potent safe vaccine, prevents puppy Parvo virus deaths and lost kennel revenues.
Sanitation can be achieved through thorough cleaning and the use of proper disinfectants. Bleach is the most common; however, it is not the safest. Bleach contains Quat Ammonias, an ingredient that is proven to be harmful, even fatal, in puppies. The exposure to bleach does not always occur due to a saturated surface. Puppy’s skin, until 8 weeks of age, will absorb surface moisture, thus allowing bleach to cause gastrointestinal tract injury. Also the harmful fumes of bleach can be detected by a puppy for up to 24 hours after use. These fumes weaken the respiratory system, allowing harmful viruses, such as Bordetella, to set up. The safest and most effective disinfectant is Oxine AH. Oxine has no withdrawal time, while still killing all forms of Parvo. Oxine is a powerful sanitizer which has been tested to be 10 times more effective than bleach, while still being the safest disinfectant on the market. Safe enough to sanitize water on cruise ships and the air in airplanes.
If you have any questions, please feel free to contact our knowledgeable customer service team at 1-800-979-2869.